Hi,
if it gets detected you should use the right option of pysim to interact with a tty based reader instead of the pcscd based reader.
from the help output (pysim-read.ph -h):
Serial Reader:
-d DEV, --device DEV Serial Device for SIM access (default: /dev/ttyUSB0)
-b BAUD, --baud BAUD Baud rate used for SIM access (default: 9600)
PC/SC Reader:
-p PCSC, --pcsc-device PCSC
PC/SC reader number to use for SIM access (default: None)
Cheers
Bjoern